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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC4A1 All Species: 6.36
Human Site: S303 Identified Species: 17.5
UniProt: P02730 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.38
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P02730 NP_000333.1 911 101792 S303 I D A Y M A Q S R G E L L H S
Chimpanzee Pan troglodytes XP_511548 900 100325 L270 I R F L F V L L G P E A P H I
Rhesus Macaque Macaca mulatta XP_001103478 1172 130022 E525 E A A Y L A D E R D D L L T A
Dog Lupus familis XP_532761 1223 134633 E589 E A A Y L A D E R E D L L T A
Cat Felis silvestris
Mouse Mus musculus P04919 929 103117 N316 I T A S M A H N R E E L L R S
Rat Rattus norvegicus P23562 927 103154 S316 V T A S L A Q S R G E L L S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P15575 922 102205 G310 R D A Y L C G G R A E L L G G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001107912 1232 137883 D593 E A A Y L A D D R Q D L L N A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791964 1247 140119 S587 E T A Y Q A E S M R D L L T A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.2 49.3 45.7 N.A. 81.3 81.4 N.A. N.A. 61.8 N.A. 47.8 N.A. N.A. N.A. N.A. 36.4
Protein Similarity: 100 93 62.8 58.5 N.A. 88.1 89.2 N.A. N.A. 74.6 N.A. 60 N.A. N.A. N.A. N.A. 51.1
P-Site Identity: 100 20 40 40 N.A. 60 66.6 N.A. N.A. 46.6 N.A. 40 N.A. N.A. N.A. N.A. 40
P-Site Similarity: 100 20 60 60 N.A. 66.6 80 N.A. N.A. 53.3 N.A. 66.6 N.A. N.A. N.A. N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 34 89 0 0 78 0 0 0 12 0 12 0 0 45 % A
% Cys: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 23 0 0 0 0 34 12 0 12 45 0 0 0 0 % D
% Glu: 45 0 0 0 0 0 12 23 0 23 56 0 0 0 0 % E
% Phe: 0 0 12 0 12 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 12 12 12 23 0 0 0 12 12 % G
% His: 0 0 0 0 0 0 12 0 0 0 0 0 0 23 0 % H
% Ile: 34 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 12 56 0 12 12 0 0 0 89 89 0 0 % L
% Met: 0 0 0 0 23 0 0 0 12 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 12 0 0 0 0 0 12 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 12 0 0 12 0 0 % P
% Gln: 0 0 0 0 12 0 23 0 0 12 0 0 0 0 0 % Q
% Arg: 12 12 0 0 0 0 0 0 78 12 0 0 0 12 0 % R
% Ser: 0 0 0 23 0 0 0 34 0 0 0 0 0 12 34 % S
% Thr: 0 34 0 0 0 0 0 0 0 0 0 0 0 34 0 % T
% Val: 12 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 67 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _